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Clinical Trials in a Dish: The Potential of Pluripotent Stem Cells to Develop Therapies for Neurodegenerative Diseases

Neurodegenerative diseases are a leading cause of death. No disease-modifying therapies are available, and preclinical animal model data have routinely failed to translate into success for therapeutics. Induced pluripotent stem cell (iPSC) biology holds great promise for human in vitro disease model...

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Podrobná bibliografie
Vydáno v:Annu Rev Pharmacol Toxicol
Hlavní autoři: Haston, Kelly M., Finkbeiner, Steven
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868344/
https://ncbi.nlm.nih.gov/pubmed/26514199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-pharmtox-010715-103548
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