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N-Alpha-Acetyltransferases and Regulation of CFTR Expression

The majority of cystic fibrosis (CF)-causing mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) lead to the misfolding, mistrafficking, and degradation of the mutant protein. Inhibition of degradation does not effectively increase the amount of trafficking competent CFTR, bu...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Vetter, Ali J., Karamyshev, Andrey L., Patrick, Anna E., Hudson, Henry, Thomas, Philip J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868295/
https://ncbi.nlm.nih.gov/pubmed/27182737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0155430
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