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Testing for Hardy–Weinberg equilibrium at biallelic genetic markers on the X chromosome

Testing genetic markers for Hardy–Weinberg equilibrium (HWE) is an important tool for detecting genotyping errors in large-scale genotyping studies. For markers at the X chromosome, typically the χ(2) or exact test is applied to the females only, and the hemizygous males are considered to be uninfor...

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Detalhes bibliográficos
Publicado no:Heredity (Edinb)
Main Authors: Graffelman, J, Weir, B S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868269/
https://ncbi.nlm.nih.gov/pubmed/27071844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/hdy.2016.20
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