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Global analysis of protein expression and phosphorylation levels in nicotine-treated pancreatic stellate cells

Smoking is a risk factor in pancreatic disease, however, the biochemical mechanisms correlating smoking with pancreatic dysfunction remain poorly understood. Strategies using multiplexed isobaric tag-based mass spectrometry facilitate the study of drug-induced perturbations on biological systems. He...

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Détails bibliographiques
Publié dans:J Proteome Res
Auteurs principaux: Paulo, Joao A., Gaun, Aleksandr, Gygi, Steven P.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868188/
https://ncbi.nlm.nih.gov/pubmed/26265067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.5b00398
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