Large-Effect Beneficial Synonymous Mutations Mediate Rapid and Parallel Adaptation in a Bacterium

Contrary to previous understanding, recent evidence indicates that synonymous codon changes may sometimes face strong selection. However, it remains difficult to generalize the nature, strength, and mechanism(s) of such selection. Previously, we showed that synonymous variants of a key enzyme-coding...

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Detalhes bibliográficos
Publicado no:Mol Biol Evol
Main Authors: Agashe, Deepa, Sane, Mrudula, Phalnikar, Kruttika, Diwan, Gaurav D., Habibullah, Alefiyah, Martinez-Gomez, Norma Cecilia, Sahasrabuddhe, Vinaya, Polachek, William, Wang, Jue, Chubiz, Lon M., Marx, Christopher J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Discoveries
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868122/
https://ncbi.nlm.nih.gov/pubmed/26908584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msw035
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