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Screening of cytoprotectors against methotrexate-induced cytogenotoxicity from bioactive phytochemicals
As a well known anti-neoplastic drug, the cytogenotoxicity of methotrexate (MTX) has received more attention in recent years. To develop a new cytoprotector to reduce the risk of second cancers caused by methotrexate, an umu test combined with a micronucleus assay was employed to estimate the cytopr...
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Udgivet i: | PeerJ |
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Main Authors: | , , |
Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
PeerJ Inc.
2016
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4867711/ https://ncbi.nlm.nih.gov/pubmed/27190706 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.1983 |
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