α-Amanitin Restrains Cancer Relapse from Drug-Tolerant Cell Subpopulations via TAF15

Cancer relapse occurs with substantial frequency even after treatment with curative intent. Here we studied drug-tolerant colonies (DTCs), which are subpopulations of cancer cells that survive in the presence of drugs. Proteomic characterization of DTCs identified stemness- and epithelial-dominant s...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kume, Kohei, Ikeda, Miyuki, Miura, Sawako, Ito, Kohei, Sato, Kei A., Ohmori, Yukimi, Endo, Fumitaka, Katagiri, Hirokatsu, Ishida, Kaoru, Ito, Chie, Iwaya, Takeshi, Nishizuka, Satoshi S.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4867652/
https://ncbi.nlm.nih.gov/pubmed/27181033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25895
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