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Simultaneous deactivation of FAK and Src improves the pathology of hypertrophic scar

Hypertrophic scar (HS) is a serious fibrotic skin condition with currently no satisfactory therapy due to undefined molecular mechanism. FAK and Src are two important non-receptor tyrosine kinases that have been indicated in HS pathogenesis. Here we found both FAK and Src were activated in HS vs. no...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Su, Linlin, Li, Xiaodong, Wu, Xue, Hui, Bo, Han, Shichao, Gao, Jianxin, Li, Yan, Shi, Jihong, Zhu, Huayu, Zhao, Bin, Hu, Dahai
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4867599/
https://ncbi.nlm.nih.gov/pubmed/27181267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26023
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