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Tissue Plasminogen Activator Neurotoxicity is Neutralized by Recombinant ADAMTS 13
Tissue plasminogen activator (tPA) is an effective treatment for ischemic stroke, but its neurotoxicity is a significant problem. Here we tested the hypothesis that recombinant ADAMTS 13 (rADAMTS 13) would reduce tPA neurotoxicity in a mouse model of stroke. We show that treatment with rADAMTS 13 in...
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| Publicado en: | Sci Rep |
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| Autores principales: | , , , , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4867598/ https://ncbi.nlm.nih.gov/pubmed/27181025 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25971 |
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