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Global quantitative proteomics reveal up-regulation of endoplasmic reticulum stress response proteins upon depletion of eIF5A in HeLa cells

The eukaryotic translation factor, eIF5A, is a translation factor essential for protein synthesis, cell growth and animal development. By use of a adenoviral eIF5A shRNA, we have achieved an effective depletion of eIF5A in HeLa cells and undertook in vivo comprehensive proteomic analyses to examine...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Mandal, Ajeet, Mandal, Swati, Park, Myung Hee
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4867578/
https://ncbi.nlm.nih.gov/pubmed/27180817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25795
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