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Design, Synthesis, and Evaluation of Donepezil-Like Compounds as AChE and BACE-1 Inhibitors
[Image: see text] An ecofriendly synthetic pathway for the synthesis of donepezil precursors is described. Alternative energy sources were used for the total synthesis in order to improve yields, regioselectively, and rate of each synthetic step and to reduce the coproduction of waste at the same ti...
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Publicado no: | ACS Med Chem Lett |
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Main Authors: | , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Chemical
Society
2016
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4867475/ https://ncbi.nlm.nih.gov/pubmed/27190595 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.5b00483 |
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