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De novo dominant variants affecting the motor domain of KIF1A are a cause of PEHO syndrome

PEHO syndrome (OMIM no. 260565) is characterized by myoclonic jerking and infantile spasms, profound psychomotor retardation with the absence of motor milestones and speech, absence or early loss of visual fixation with atrophy of optic discs by 2 years of age and progressive brain atrophy on neuroi...

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Detalhes bibliográficos
Publicado no:Eur J Hum Genet
Main Authors: Langlois, Sylvie, Tarailo-Graovac, Maja, Sayson, Bryan, Drögemöller, Britt, Swenerton, Anne, Ross, Colin JD, Wasserman, Wyeth W, van Karnebeek, Clara DM
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4867456/
https://ncbi.nlm.nih.gov/pubmed/26486474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2015.217
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