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A novel approach for emerging and antibiotic resistant infections: Innate Defense Regulators as an agnostic therapy

Innate Defense Regulators (IDRs) are short synthetic peptides that target the host innate immune system via an intracellular adaptor protein which functions at key signaling nodes. In this work, further details of the mechanism of action of IDRs have been discovered. The studies reported here show t...

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Detalhes bibliográficos
Publicado no:J Biotechnol
Main Authors: North, John R., Takenaka, Shunsuke, Rozek, Annett, Kielczewska, Agnieszka, Opal, Steven, Morici, Lisa A., Finlay, B. Brett, Schaber, Christopher J., Straube, Richard, Donini, Oreola
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4867239/
https://ncbi.nlm.nih.gov/pubmed/27015977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbiotec.2016.03.032
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