HMGB1 and its hyper-acetylated isoform are sensitive and specific serum biomarkers to detect asbestos exposure and to identify mesothelioma patients

PURPOSE: To determine whether serum levels of High Mobility Group Box Protein-1 (HMGB1) could differentiate malignant mesothelioma (MM) patients, asbestos-exposed individuals, and unexposed controls. EXPERIMENTAL DESIGN: Hyper-acetylated and non-acetylated HMGB1 (together referred to as total HMGB1)...

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I publikationen:Clin Cancer Res
Huvudupphovsmän: Napolitano, Andrea, Antoine, Daniel J., Pellegrini, Laura, Baumann, Francine, Pagano, Ian, Pastorino, Sandra, Goparaju, Chandra M., Prokrym, Kirill, Canino, Claudia, Pass, Harvey I., Carbone, Michele, Yang, Haining
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2016
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4867109/
https://ncbi.nlm.nih.gov/pubmed/26733616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-1130
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