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Evolution of the α-Subunit of Na/K-ATPase from Paramecium to Homo sapiens: Invariance of Transmembrane Helix Topology

Na/K-ATPase is a key plasma membrane enzyme involved in cell signaling, volume regulation, and maintenance of electrochemical gradients. The α-subunit, central to these functions, belongs to a large family of P-type ATPases. Differences in transmembrane (TM) helix topology, sequence homology, helix–...

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Detalhes bibliográficos
Publicado no:J Mol Evol
Main Authors: Morrill, Gene A., Kostellow, Adele B., Liu, Lijun, Gupta, Raj K., Askari, Amir
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4866997/
https://ncbi.nlm.nih.gov/pubmed/26961431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00239-016-9732-1
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