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Bone marrow-derived fibrocytes contribute to liver fibrosis

Chronic liver injury often leads to hepatic fibrosis, a condition associated with increased levels of circulating TGF-β1 and lipopolysaccharide, activation of myofibroblasts, and extensive deposition of extracellular matrix, mostly collagen Type I. Hepatic stellate cells are considered to be the maj...

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Detalhes bibliográficos
Publicado no:Exp Biol Med (Maywood)
Main Authors: Xu, Jun, Kisseleva, Tatiana
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4866973/
https://ncbi.nlm.nih.gov/pubmed/25966982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370215584933
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