Decreased N-acetyl-aspartate/choline ratio and increased lactate in the frontal lobe of patients with Huntington's disease: a proton magnetic resonance spectroscopy study.

BACKGROUND: Both the effect of the mutation and the pathogenesis of Huntington's disease are unknown and a lack of biological markers for the natural history of the disease impedes the evaluation of novel therapeutic approaches. METHODS: Proton magnetic resonance spectroscopy was carried out on...

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Detalhes bibliográficos
Publicado no:J Neurol Neurosurg Psychiatry
Main Authors: Harms, L, Meierkord, H, Timm, G, Pfeiffer, L, Ludolph, A C
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 1997
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC486691/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9010396/
https://ncbi.nlm.nih.govhttps://doi.org/10.1136/jnnp.62.1.27
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