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Suppression of Adipocyte Differentiation by Foenumoside B from Lysimachia foenum-graecum Is Mediated by PPARγ Antagonism

Lysimachia foenum-graecum extract (LFE) and its active component foenumoside B (FSB) have been shown to inhibit adipocyte differentiation, but their mechanisms were poorly defined. Here, we investigated the molecular mechanisms responsible for their anti-adipogenic effects. Both LFE and FSB inhibite...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kwak, Hyun Jeong, Choi, Hye-Eun, Jang, Jinsun, Park, Soo Kyoung, Cho, Byoung Heon, Kim, Seul Ki, Lee, Sunyi, Kang, Nam Sook, Cheon, Hyae Gyeong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4866755/
https://ncbi.nlm.nih.gov/pubmed/27176632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0155432
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