The histone chaperone CAF-1 safeguards somatic cell identity

Cellular differentiation involves profound remodeling of chromatic landscapes, yet the mechanisms by which somatic cell identity is subsequently maintained remain incompletely understood. To further elucidate regulatory pathways that safeguard the somatic state, we performed two comprehensive RNAi s...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Cheloufi, Sihem, Elling, Ulrich, Hopfgartner, Barbara, Jung, Youngsook L, Murn, Jernej, Ninova, Maria, Hubmann, Maria, Badeaux, Aimee I, Ang, Cheen Euong, Tenen, Danielle, Wesche, Daniel J, Abazova, Nadezhda, Hogue, Max, Tasdemir, Nilgun, Brumbaugh, Justin, Rathert, Philipp, Jude, Julian, Ferrari, Francesco, Blanco, Andres, Fellner, Michaela, Wenzel, Daniel, Zinner, Marietta, Vidal, Simon E, Bell, Oliver, Stadtfeld, Matthias, Chang, Howard Y., Almouzni, Genevieve, Lowe, Scott W, Rinn, John, Wernig, Marius, Aravin, Alexei, Shi, Yang, Park, Peter, Penninger, Josef M, Zuber, Johannes, Hochedlinger, Konrad
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4866648/
https://ncbi.nlm.nih.gov/pubmed/26659182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature15749
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