Pre-existence and Persistence of Resistant Minority Hepatitis C Virus Variants in Genotype 1-Infected Patients Treated With Simeprevir/Peginterferon/Ribavirin

Background. The pre-existence of minority hepatitis C virus (HCV) variants and their impact on treatment outcome, as well as the persistence of emerging resistant variants posttreatment in patients failing treatment with simeprevir/peginterferon/ribavirin (SMV/PR), were assessed by deep sequencing (...

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Detalhes bibliográficos
Publicado no:Open Forum Infect Dis
Main Authors: Fevery, Bart, Thys, Kim, Van Eygen, Veerle, Verbinnen, Thierry, Van Rossem, Elizabeth, Buelens, Annemie, Aerssens, Jeroen, Witek, James, Picchio, Gaston, De Meyer, Sandra, Lenz, Oliver
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
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Major Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4866569/
https://ncbi.nlm.nih.gov/pubmed/27186579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofw052
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