Structure and dynamics of des-pentapeptide-insulin in solution: the molten-globule hypothesis.
Structures of insulin in different crystal forms exhibit significant local and nonlocal differences, including correlated displacement of elements of secondary structure. Here we describe the solution structure and dynamics of a monomeric insulin analogue, des-pentapeptide-(B26-B30)-insulin (DPI), a...
Enregistré dans:
| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
1992
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48661/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1549601/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.6.2379 |
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