The incidence of leukaemia in women with BRCA1 and BRCA2 mutations: an International Prospective Cohort Study

BACKGROUND: Germline mutations in BRCA1 and BRCA2 increase the susceptibility to develop breast and ovarian cancers as well as increase the risk of some other cancers. Primary objective was to estimate the risk of leukaemia in BRCA1 and BRCA2 mutation carriers. METHODS: We followed 7243 women with a...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Iqbal, Javaid, Nussenzweig, Andre, Lubinski, Jan, Byrski, Tomasz, Eisen, Andrea, Bordeleau, Louise, Tung, Nadine M, Manoukian, Siranoush, Phelan, Catherine M, Sun, Ping, Narod, Steven A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Genetics and Genomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4865972/
https://ncbi.nlm.nih.gov/pubmed/26986251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2016.58
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