Estrogen Enhances Linkage in the Vascular Endothelial Calmodulin Network via a Feedforward Mechanism at the G Protein-coupled Estrogen Receptor 1

Estrogen exerts many effects on the vascular endothelium. Calmodulin (CaM) is the transducer of Ca(2+) signals and is a limiting factor in cardiovascular tissues. It is unknown whether and how estrogen modifies endothelial functions via the network of CaM-dependent proteins. Here we show that 17β-es...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Tran, Quang-Kim, Firkins, Rachel, Giles, Jennifer, Francis, Sarah, Matnishian, Vahe, Tran, Phuong, VerMeer, Mark, Jasurda, Jake, Burgard, Michelle Ann, Gebert-Oberle, Briana
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4865926/
https://ncbi.nlm.nih.gov/pubmed/26987903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.697334
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