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The Gas6-Axl Protein Interaction Mediates Endothelial Uptake of Platelet Microparticles

Upon activation, platelets release plasma membrane-derived microparticles (PMPs) exposing phosphatidylserine on their surface. The functions and clearance mechanism of these microparticles are incompletely understood. As they are pro-coagulant and potentially pro-inflammatory, rapid clearance from t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Happonen, Kaisa E., Tran, Sinh, Mörgelin, Matthias, Prince, Raja, Calzavarini, Sara, Angelillo-Scherrer, Anne, Dahlbäck, Björn
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4865908/
https://ncbi.nlm.nih.gov/pubmed/27006397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.699058
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