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Slug-upregulated miR-221 promotes breast cancer progression through suppressing E-cadherin expression
It is generally regarded that E-cadherin is downregulated during tumorigenesis via Snail/Slug-mediated E-cadherin transcriptional reduction. However, this transcriptional suppressive mechanism cannot explain the failure of producing E-cadherin protein in metastatic breast cancer cells after overexpr...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4865839/ https://ncbi.nlm.nih.gov/pubmed/27174021 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25798 |
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