Sequential and compartmentalized action of Rabs, SNAREs, and MAL in the apical delivery of fusiform vesicles in urothelial umbrella cells

Uroplakins (UPs) are major differentiation products of urothelial umbrella cells and play important roles in forming the permeability barrier and in the expansion/stabilization of the apical membrane. Further, UPIa serves as a uropathogenic Escherichia coli receptor. Although it is understood that U...

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Veröffentlicht in:Mol Biol Cell
Hauptverfasser: Wankel, Bret, Ouyang, Jiangyong, Guo, Xuemei, Hadjiolova, Krassimira, Miller, Jeremy, Liao, Yi, Tham, Daniel Kai Long, Romih, Rok, Andrade, Leonardo R., Gumper, Iwona, Simon, Jean-Pierre, Sachdeva, Rakhee, Tolmachova, Tanya, Seabra, Miguel C., Fukuda, Mitsunori, Schaeren-Wiemers, Nicole, Hong, Wan Jin, Sabatini, David D., Wu, Xue-Ru, Kong, Xiangpeng, Kreibich, Gert, Rindler, Michael J., Sun, Tung-Tien
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4865319/
https://ncbi.nlm.nih.gov/pubmed/27009205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-04-0230
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