The unusual synergism of transferrin and citrate in the regulation of Ti(IV) speciation, transport, and toxicity

Human serum transferrin (sTf) is a protein that mediates the transport of iron from blood to cells. Assisted by the synergistic anion carbonate sTf transports Fe(III) by binding the metal ion in a closed conformation. Previous studies suggest sTf’s role as a potential transporter of other metals lik...

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Pubblicato in:J Am Chem Soc
Autori principali: Tinoco, Arthur D., Saxena, Manoj, Sharma, Shweta, Noinaj, Nicholas, Delgado, Yamixa, Quiñones González, Ernesto P., Conklin, Steven E., Zambrana, Nicole, Loza-Rosas, Sergio A., Parks, Timothy B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4865248/
https://ncbi.nlm.nih.gov/pubmed/27070073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b01966
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