Maternal Smoking during Pregnancy and DNA-Methylation in Children at Age 5.5 Years: Epigenome-Wide-Analysis in the European Childhood Obesity Project (CHOP)-Study

Mounting evidence links prenatal exposure to maternal tobacco smoking with disruption of DNA methylation (DNAm) profile in the blood of infants. However, data on the postnatal stability of such DNAm signatures in childhood, as assessed by Epigenome Wide Association Studies (EWAS), are scarce. Object...

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Publicat a:PLoS One
Autors principals: Rzehak, Peter, Saffery, Richard, Reischl, Eva, Covic, Marcela, Wahl, Simone, Grote, Veit, Xhonneux, Annick, Langhendries, Jean-Paul, Ferre, Natalia, Closa-Monasterolo, Ricardo, Verduci, Elvira, Riva, Enrica, Socha, Piotr, Gruszfeld, Dariusz, Koletzko, Berthold
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4865176/
https://ncbi.nlm.nih.gov/pubmed/27171005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0155554
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