A Novel Method for Gene-Specific Enhancement of Protein Translation by Targeting 5’UTRs of Selected Tumor Suppressors

BACKGROUND: Translational control is a mechanism of protein synthesis regulation emerging as an important target for new therapeutics. Naturally occurring microRNAs and synthetic small inhibitory RNAs (siRNAs) are the most recognized regulatory molecules acting via RNA interference. Surprisingly, re...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Master, Adam, Wójcicka, Anna, Giżewska, Kamilla, Popławski, Piotr, Williams, Graham R., Nauman, Alicja
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4865139/
https://ncbi.nlm.nih.gov/pubmed/27171412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0155359
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