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Bombesin-like receptor 3 regulates blood pressure and heart rate via a central sympathetic mechanism

Bombesin-like receptor 3 (BRS-3) is an orphan G protein-coupled receptor that regulates energy expenditure, food intake, and body weight. We examined the effects of BRS-3 deletion and activation on blood pressure and heart rate. In free-living, telemetered Brs3 null mice the resting heart rate was 1...

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Détails bibliographiques
Publié dans:Am J Physiol Heart Circ Physiol
Auteurs principaux: Lateef, Dalya M., Xiao, Cuiying, Brychta, Robert J., Diedrich, André, Schnermann, Jurgen, Reitman, Marc L.
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2016
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4865066/
https://ncbi.nlm.nih.gov/pubmed/26801314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00963.2015
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