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The epigenetic clock and telomere length are independently associated with chronological age and mortality

BACKGROUND: Telomere length and DNA methylation have been proposed as biological clock measures that track chronological age. Whether they change in tandem, or contribute independently to the prediction of chronological age, is not known. METHODS: We address these points using data from two Scottish...

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Bibliografiske detaljer
Udgivet i:Int J Epidemiol
Main Authors: Marioni, Riccardo E, Harris, Sarah E, Shah, Sonia, McRae, Allan F, von Zglinicki, Thomas, Martin-Ruiz, Carmen, Wray, Naomi R, Visscher, Peter M, Deary, Ian J
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2016
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4864882/
https://ncbi.nlm.nih.gov/pubmed/27075770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ije/dyw041
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