Mice Lacking the Serotonin Htr(2B) Receptor Gene Present an Antipsychotic-Sensitive Schizophrenic-Like Phenotype

Impulsivity and hyperactivity share common ground with numerous mental disorders, including schizophrenia. Recently, a population-specific serotonin 2B (5-HT(2B)) receptor stop codon (ie, HTR2B Q20*) was reported to segregate with severely impulsive individuals, whereas 5-HT(2B) mutant (Htr(2B)(−/−)...

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Publicado en:Neuropsychopharmacology
Autores principales: Pitychoutis, Pothitos M, Belmer, Arnauld, Moutkine, Imane, Adrien, Joëlle, Maroteaux, Luc
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2015
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4864652/
https://ncbi.nlm.nih.gov/pubmed/25936642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2015.126
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