Serotonin Transporter and Tryptophan Hydroxylase Gene Variations Mediate Working Memory Deficits of Cocaine Users

Cocaine users consistently develop working memory (WM) impairments but the mediating molecular mechanisms are unknown so far. Recent evidence suggests that the serotonin (5-HT) system is altered by chronic cocaine use, while also being involved in WM processing. Thus, we investigated the effects of...

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Detalhes bibliográficos
Publicado no:Neuropsychopharmacology
Main Authors: Havranek, Michael M, Vonmoos, Matthias, Müller, Christian P, Büetiger, Jessica R, Tasiudi, Eve, Hulka, Lea M, Preller, Katrin H, Mössner, Rainald, Grünblatt, Edna, Seifritz, Erich, Quednow, Boris B
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4864628/
https://ncbi.nlm.nih.gov/pubmed/26013962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2015.146
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