nanoCAGE reveals 5′ UTR features that define specific modes of translation of functionally related MTOR-sensitive mRNAs

The diversity of MTOR-regulated mRNA translation remains unresolved. Whereas ribosome-profiling suggested that MTOR almost exclusively stimulates translation of the TOP (terminal oligopyrimidine motif) and TOP-like mRNAs, polysome-profiling indicated that MTOR also modulates translation of mRNAs wit...

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Dades bibliogràfiques
Publicat a:Genome Res
Autors principals: Gandin, Valentina, Masvidal, Laia, Hulea, Laura, Gravel, Simon-Pierre, Cargnello, Marie, McLaughlan, Shannon, Cai, Yutian, Balanathan, Preetika, Morita, Masahiro, Rajakumar, Arjuna, Furic, Luc, Pollak, Michael, Porco, John A., St-Pierre, Julie, Pelletier, Jerry, Larsson, Ola, Topisirovic, Ivan
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2016
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4864462/
https://ncbi.nlm.nih.gov/pubmed/26984228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.197566.115
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