Isorhapontigenin suppresses growth of patient-derived glioblastoma spheres through regulating miR-145/SOX2/cyclin D1 axis

BACKGROUND: Glioblastoma (GBM) is the most common malignant brain tumor, and glioma stem cells (GSCs) are considered a major source of treatment resistance for glioblastoma. Identifying new compounds that inhibit the growth of GSCs and understanding their underlying molecular mechanisms are therefor...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Xu, Zhou, Zeng, Xingruo, Xu, Jiawei, Xu, Derek, Li, Jingxia, Jin, Honglei, Jiang, Guosong, Han, Xiaosi, Huang, Chuanshu
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4864260/
https://ncbi.nlm.nih.gov/pubmed/26681767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nov298
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