CD4(+) T effector memory cell dysfunction is associated with the accumulation of granulocytic myeloid-derived suppressor cells in glioblastoma patients

BACKGROUND: Myeloid-derived suppressor cells (MDSCs) comprise a heterogeneous population of myeloid cells that are significantly expanded in cancer patients and are associated with tumor progression. METHODS: Multicolor flow cytometry was used to study the frequency, phenotype, and function of MDSCs...

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Publicado en:Neuro Oncol
Autores principales: Dubinski, Daniel, Wölfer, Johannes, Hasselblatt, Martin, Schneider-Hohendorf, Tilman, Bogdahn, Ulrich, Stummer, Walter, Wiendl, Heinz, Grauer, Oliver M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2016
Materias:
Basic and Translational Investigations
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4864257/
https://ncbi.nlm.nih.gov/pubmed/26578623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nov280
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