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CD4(+) T effector memory cell dysfunction is associated with the accumulation of granulocytic myeloid-derived suppressor cells in glioblastoma patients

BACKGROUND: Myeloid-derived suppressor cells (MDSCs) comprise a heterogeneous population of myeloid cells that are significantly expanded in cancer patients and are associated with tumor progression. METHODS: Multicolor flow cytometry was used to study the frequency, phenotype, and function of MDSCs...

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Bibliografske podrobnosti
izdano v:Neuro Oncol
Main Authors: Dubinski, Daniel, Wölfer, Johannes, Hasselblatt, Martin, Schneider-Hohendorf, Tilman, Bogdahn, Ulrich, Stummer, Walter, Wiendl, Heinz, Grauer, Oliver M.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4864257/
https://ncbi.nlm.nih.gov/pubmed/26578623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nov280
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