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HIV-associated CD4/8 depletion in infancy is associated with neurometabolic reductions in the basal ganglia at age 5 years despite early antiretroviral therapy

OBJECTIVE: Investigating consequences of early or late antiretroviral therapy (ART) initiation in infancy on young brain development using magnetic resonance spectroscopy (MRS). DESIGN: Most pediatric HIV/ART-related neurological studies are from neuropsychological/clinical perspectives. MRS can elu...

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Detalhes bibliográficos
Publicado no:AIDS
Main Authors: MBUGUA, Kenneth K., HOLMES, Martha J., COTTON, Mark F., RATAI, Eva-Maria, LITTLE, Francesca, HESS, Aaron. T., DOBBELS, Els, VAN DER KOUWE, Andre J.W., LAUGHTON, Barbara, MEINTJES, Ernesta M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4864158/
https://ncbi.nlm.nih.gov/pubmed/26959509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000001082
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