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2-Deoxy–D-Glucose (2-DG) Induced Cardiac Toxicity in Rat: NT- proBNP and BNP as Potential Early Cardiac Safety Biomarkers

2- Deoxy–D-Glucose (2-DG) is being developed as a potential anticonvulsant and disease-modifying agent for epilepsy patients; however, during preclinical development, cardiac toxicity has been encountered in rats. This study was performed to determine whether cardiac troponin (cTnI and cTnT), Atrial...

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Detalhes bibliográficos
Publicado no:Int J Toxicol
Main Authors: Terse, PS, Joshi, PS, Bordelon, NR, Brys, AM, Patton, KM, Arndt, TP, Sutula, TP
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4864115/
https://ncbi.nlm.nih.gov/pubmed/26838190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1091581815624397
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