A bacterial toxin and a non-enveloped virus hijack ER-to-cytosol membrane translocation pathways to cause disease

A dedicated network of cellular factors ensures that proteins translocated into the endoplasmic reticulum (ER) are folded correctly before they exit this compartment en route to other cellular destinations or for secretion. When proteins misfold, selective ER-resident enzymes and chaperones are recr...

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Bibliographic Details
Published in:Crit Rev Biochem Mol Biol
Main Authors: He, Kaiyu, Ravindran, Madhu Sudhan, Tsai, Billy
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4864032/
https://ncbi.nlm.nih.gov/pubmed/26362261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10409238.2015.1085826
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