Pharmacological Reprogramming of Fibroblasts into Neural Stem Cells by Signaling-Directed Transcriptional Activation

Cellular reprogramming using chemically defined conditions, without genetic manipulation, is a promising approach for generating clinically relevant cell types for regenerative medicine and drug discovery. However, small molecule approaches for inducing lineage-specific stem cells from somatic cells...

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Vydáno v:Cell Stem Cell
Hlavní autoři: Zhang, Mingliang, Lin, Yuan-Hung, Sun, Yujiao Jennifer, Zhu, Saiyong, Zheng, Jiashun, Liu, Kai, Cao, Nan, Li, Ke, Huang, Yadong, Ding, Sheng
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4864020/
https://ncbi.nlm.nih.gov/pubmed/27133794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2016.03.020
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