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Structure and Properties of fac-[Re(I)(CO)(3)(NTA)](2−) (NTA(3−) = Tri-anion of Nitrilotriacetic Acid) and fac-[Re(I)(CO)(3)(L)](n−) Analogs Useful for Assessing the Excellent Renal Clearance of the fac-[(99m)Tc(I)(CO)(3)(NTA)](2−) Diagnostic Renal Agent

We previously identified two new agents based on the [(99m)Tc(V)O](3+) core with renal clearances in human volunteers 30% higher than that of the widely used clinical tracer (99m)Tc-MAG(3) (MAG(3)(5−) = penta-anion of mercaptoacetyltriglycine). However, renal agents with even higher clearances are n...

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Détails bibliographiques
Publié dans:Inorg Chem
Auteurs principaux: Klenc, Jeffrey, Lipowska, Malgorzata, Abhayawardhana, Pramuditha L., Taylor, Andrew T., Marzilli, Luigi G.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4863976/
https://ncbi.nlm.nih.gov/pubmed/26068141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.inorgchem.5b00584
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