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Where, How, and When: Positioning Posttranslational Modification Within Type 1 Diabetes Pathogenesis

Autoreactive T cells specific for islet autoantigens develop in type 1 diabetes (T1D) by escaping central as well as peripheral tolerance. The current paradigm for development of islet autoimmunity is just beginning to include the contribution of posttranslationally modified (PTM) islet autoantigens...

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Publicat a:Curr Diab Rep
Autors principals: McLaughlin, Rene J., Spindler, Matthew P., van Lummel, Menno, Roep, Bart O.
Format: Artigo
Idioma:Inglês
Publicat: Springer US 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4863913/
https://ncbi.nlm.nih.gov/pubmed/27168063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11892-016-0752-4
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