HIF3A association with adiposity: the story begins before birth

AIM: Determine if the association of HIF3A DNA methylation with weight and adiposity is detectable early in life. MATERIAL & METHODS: We determined HIF3A genotype and DNA methylation patterns (on hybridization arrays) in DNA extracted from umbilical cords of 991 infants. Methylation levels at th...

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Veröffentlicht in:Epigenomics
Hauptverfasser: Pan, Hong, Lin, Xinyi, Wu, Yonghui, Chen, Li, Teh, Ai Ling, Soh, Shu E, Lee, Yung Seng, Tint, Mya Thway, MacIsaac, Julia L, Morin, Alexander M, Tan, Kok Hian, Yap, Fabian, Saw, Seang Mei, Kobor, Michael S, Meaney, Michael J, Godfrey, Keith M, Chong, Yap-Seng, Gluckman, Peter D, Karnani, Neerja, Holbrook, Joanna D
Format: Artigo
Sprache:Inglês
Veröffentlicht: Future Medicine Ltd 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4863876/
https://ncbi.nlm.nih.gov/pubmed/26011824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/epi.15.45
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