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Theaflavin-3, 3′-digallate induces apoptosis and G2 cell cycle arrest through the Akt/MDM2/p53 pathway in cisplatin-resistant ovarian cancer A2780/CP70 cells

Ovarian cancer is the most lethal gynecological cancer among women worldwide. Adverse side effects and acquired resistance to conventional platinum based chemotherapy are major impediments in ovarian cancer treatment, and drive the development of more selective anticancer drugs that target cancer-sp...

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Dettagli Bibliografici
Pubblicato in:Int J Oncol
Autori principali: TU, YOUYING, KIM, EUNHYE, GAO, YING, RANKIN, GARY O., LI, BO, CHEN, YI CHARLIE
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4863729/
https://ncbi.nlm.nih.gov/pubmed/27082635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2016.3472
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