Population-Scale Sequencing Data Enable Precise Estimates of Y-STR Mutation Rates

Short tandem repeats (STRs) are mutation-prone loci that span nearly 1% of the human genome. Previous studies have estimated the mutation rates of highly polymorphic STRs by using capillary electrophoresis and pedigree-based designs. Although this work has provided insights into the mutational dynam...

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Bibliografiska uppgifter
I publikationen:Am J Hum Genet
Huvudupphovsmän: Willems, Thomas, Gymrek, Melissa, Poznik, G. David, Tyler-Smith, Chris, Erlich, Yaniv
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2016
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4863667/
https://ncbi.nlm.nih.gov/pubmed/27126583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2016.04.001
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