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Galectin-3 cleavage alters bone remodeling: Different outcomes in breast and prostate cancer skeletal metastasis

Management of bone metastasis remains clinically challenging and requires the identification of new molecular target(s) that can be therapeutically exploited to improve patient outcome. Galectin-3 (Gal-3) has been implicated as a secreted factor that alters the bone tumor microenvironment. Proteolyt...

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Detalles Bibliográficos
Publicado en:Cancer Res
Main Authors: Nakajima, Kosei, Kho, Dhong Hyo, Yanagawa, Takashi, Harazono, Yosuke, Hogan, Victor, Chen, Wei, Ali-Fehmi, Rouba, Mehra, Rohit, Raz, Avraham
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4863655/
https://ncbi.nlm.nih.gov/pubmed/26837763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-1793
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