Epidemic Keratoconjunctivitis-Causing Adenoviruses Induce MUC16 Ectodomain Release To Infect Ocular Surface Epithelial Cells

Human adenoviruses (HAdV), species D in particular (HAdV-D), are frequently associated with epidemic keratoconjunctivitis (EKC). Although the infection originates at the ocular surface epithelium, the mechanisms by which HAdV-Ds bypass the membrane-associated mucin (MAM)-rich glycocalyx of the ocula...

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Pubblicato in:mSphere
Autori principali: Menon, Balaraj B., Zhou, Xiaohong, Spurr-Michaud, Sandra, Rajaiya, Jaya, Chodosh, James, Gipson, Ilene K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2016
Soggetti:
Observation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4863608/
https://ncbi.nlm.nih.gov/pubmed/27303700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.00112-15
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