Uropathogenic Escherichia coli Metabolite-Dependent Quiescence and Persistence May Explain Antibiotic Tolerance during Urinary Tract Infection

In the present study, it is shown that although Escherichia coli CFT073, a human uropathogenic (UPEC) strain, grows in liquid glucose M9 minimal medium, it fails to grow on glucose M9 minimal medium agar plates seeded with ≤10(6) CFU. The cells on glucose plates appear to be in a “quiescent” state t...

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Publicat a:mSphere
Autors principals: Leatham-Jensen, Mary P., Mokszycki, Matthew E., Rowley, David C., Deering, Robert, Camberg, Jodi L., Sokurenko, Evgeni V., Tchesnokova, Veronika L., Frimodt-Møller, Jakob, Krogfelt, Karen A., Leth Nielsen, Karen, Frimodt-Møller, Niels, Sun, Gongqin, Cohen, Paul S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4863606/
https://ncbi.nlm.nih.gov/pubmed/27303698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.00055-15
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