DNA methylation and mRNA expression of HLA‐DQA1 alleles in type 1 diabetes mellitus

Type 1 diabetes (T1D) belongs among polygenic multifactorial autoimmune diseases. The highest risk is associated with human leucocyte antigen (HLA) class II genes, including HLA‐DQA1 gene. Our aim was to investigate DNA methylation of HLA‐DQA1 promoter alleles (QAP) and correlate methylation status...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Immunology
Main Authors: Cepek, Pavel, Zajacova, Marta, Kotrbova‐Kozak, Anna, Silhova, Elena, Cerna, Marie
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2016
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4863572/
https://ncbi.nlm.nih.gov/pubmed/26854762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12593
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