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DNA methylation and mRNA expression of HLA‐DQA1 alleles in type 1 diabetes mellitus

Type 1 diabetes (T1D) belongs among polygenic multifactorial autoimmune diseases. The highest risk is associated with human leucocyte antigen (HLA) class II genes, including HLA‐DQA1 gene. Our aim was to investigate DNA methylation of HLA‐DQA1 promoter alleles (QAP) and correlate methylation status...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Immunology
Päätekijät: Cepek, Pavel, Zajacova, Marta, Kotrbova‐Kozak, Anna, Silhova, Elena, Cerna, Marie
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4863572/
https://ncbi.nlm.nih.gov/pubmed/26854762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12593
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