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Loss of miR‐182 affects B‐cell extrafollicular antibody response

MicroRNAs have been shown to play a role in B‐cell differentiation and activation. Here, we found miR‐182 to be highly induced in activated B cells. However, mice lacking miR‐182 have normal B‐cell and T‐cell development. Interestingly, mutant mice exhibited a defective antibody response at early ti...

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Bibliografische gegevens
Gepubliceerd in:Immunology
Hoofdauteurs: Li, Yan‐Feng, Ou, Xijun, Xu, Shengli, Jin, Zi‐Bing, Iwai, Naoharu, Lam, Kong‐Peng
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4863571/
https://ncbi.nlm.nih.gov/pubmed/26849109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12592
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